Hattori M, Mizuguchi H, Baba Y, Ono S, Nakano T, Zhang Q, Sasaki Y, Kobayashi M, Kitamura Y, Takeda N, Fukui H. Quercetin inhibits transcriptional up-regulation of histamine H1 receptor via suppressing protein kinase C-δ/extracellular signal-regulated kinase/poly(ADP-ribose) polymerase-1 signaling pathway in HeLa cells. Int Immunopharmacol. 2013 Feb;15(2):232-9. doi: 10.1016/j.intimp.2012.12.030. Epub 2013 Jan 16. PMID: 23333628.
Jarisch R, Weyer D, Ehlert E, Koch CH, Pinkow- ski E, Jung P, Kähler W, Girgensohn R, Kowalski J, Weisser B, Koch A. Impact of oral vitamin C on hista- mine levels and seasickness. J Vestib Res. 2014; 24(4):281-8. doi: 10.3233/VES-140509. PMID: 25095772.
Gao W, Zan Y, Wang ZJ, Hu XY, Huang F. Quercetin ameliorates...neuropathic pain by stabilizing mast cells, and subsequently blocking PKCε-dependent activation of TRPV1. Acta Pharmacol Sin. 2016 Sep;37(9):1166-77. doi: 10.1038/aps.2016.58. Epub 2016 Aug 8. PMID: 27498772; PMCID: PMC5022098.
Yang CC, Hung YL, Li HJ, Lin YF, Wang SJ, Chang DC, Pu CM, Hung CF. Quercetin inhibits histamine-induced calcium influx in human keratinocyte via histamine H4 receptors. Int Immunopharmacol. 2021 Jul;96:107620. doi: 10.1016/j.intimp.2021.107620. Epub 2021 Apr 13. PMID: 33862555.
Park HH, Lee S, Son HY, Park SB, Kim MS, Choi EJ, Singh TS, Ha JH, Lee MG, Kim JE, Hyun MC, Kwon TK, Kim YH, Kim SH. Flavonoids inhibit histamine release and expression of proinflammatory cytokines in mast cells. Arch Pharm Res. 2008 Oct;31(10):1303-11. doi: 10.1007/s12272-001-2110-5. Epub 2008 Oct 29. PMID: 18958421.
Zhang Y, Guan R, Huang H. Anti-Allergic Effects of Quercetin and Quercetin Liposomes in RBL-2H3 Cells. Endocr Metab Immune Disord Drug Targets. 2023;23(5):692-701. doi: 10.2174/1871530322666220627151830. PMID: 35761488.
Hrubisko M et al., Histamine Intolerance-The More We Know the Less
We Know. A Review. Nutrients. 2021;13(7):2228. Published 2021 Jun 29.
doi:10.3390/nu1307222
Dev S et al., Suppression of histamine signaling by probiotic Lac-B:
a possible mechanism of its anti-allergic effect. J Pharmacol Sci.
2008 Jun;107(2):159-66. doi: 10.1254/jphs.08028fp. Epub 2008 Jun 5.
PMID: 18544899.
Diesner SC et al., A distinct microbiota composition is associated with
protection from food allergy in an oral mouse immunization model.
Clin Immunol. 2016 Dec;173:10-18. doi: 10.1016/j.clim.2016.10.009. Epub
2016 Oct 24. PMID: 27789346; PMCID: PMC5464391
Schink M, Konturek PC, Tietz E, Dieterich W, Pinzer TC, Wirtz S, Neurath MF, Zopf Y. Microbial patterns in patients with histamine intolerance.J Physiol Pharmacol. 2018 Aug;69(4). doi: 10.26402/ jpp.2018.4.09. Epub 2018 Dec 9. PMID: 30552302.
Ilenia Bazzucchi, Federica Patrizio, Roberta Ceci et al. (2019). The Effects of Quercetin Supple- mentation on Eccentric Exercise-Induced Muscle7Damage. In: Nutrients 11(1), 205; https://doi.org/10.3390/nu11010205
J. M. Pauff, R. Hille: Inhibition studies of bovine xanthine oxidase by luteolin, silibinin, quercetin, and curcumin. In: Journal of natural products. Band 72, Nummer 4, April 2009, S. 725–731, doi:10.102
Clemetson CA. Histamine and ascorbic acid in human blood. J Nutr. 1980 Apr;110(4):662-8. doi: 10.1093/jn/110.4.662. PMID: 7365537.
Pfisterer M, Mayer I: Histaminintoleranz – aktueller Stand der Technik von Diagnose und Therapie. EHK 2008; 57: 110–114
Burgerstein, Handbuch Nährstoffe,13. aktualisierte Auflage 2018, Trias-Verlag, ISBN 978-3-432-10661-8
Folkers K. et al, Biochemical evidence for a deficiency of vitamin B6 in subjects reacting to monosodium L-glutamate by the Chinese Restaurant Syndrome, Biochemi. Biophys. Res. Commun. 100:972-7,1981
Mlcek J, Jurikova T, Skrovankova S, Sochor J. Quercetin and Its Anti-Allergic Immune Response. Molecules. 2016 May 12;21(5):623. doi: 10.3390/molecules21050623. PMID: 27187333; PMCID: PMC6273625.
Small, P., Keith, P.K. & Kim, H. Allergic rhinitis. Allergy Asthma Clin Immunol 14 (Suppl 2), 51 (2018). https://doi.org/10.1186/s13223-018-0280-7
Jafarinia M, Sadat Hosseini M, Kasiri N, Fazel N, Fathi F, Ganjalikhani Hakemi M, Eskandari N. Quercetin with the potential effect on allergic diseases. Allergy Asthma Clin Immunol. 2020 May 14;16:36. doi: 10.1186/s13223-020-00434-0. PMID: 32467711; PMCID: PMC7227109.
Yamada S, Shirai M, Inaba Y, Takara T. Effects of repeated oral intake of a quercetin-containing supplement on allergic reaction: a randomized, placebo-controlled, double-blind parallel group study. Eur Rev Med Pharmacol Sci. 2022:26(12):4331-4345.
Boots AW, Haenen GR, Bast A. Health effects of quercetin: from antioxidant to nutraceutical. Eur J Pharmacol. 2008;582(2-3):325-37.
Thornhill SM, Kelly AM. Natural treatment of perennial allergic rhinitis. Alt Med Rev. 2000;5(5):448-54.
Ke X, Chen Z, Wang X, Kang H, Hong S. Quercetin improves the imbalance of Th1/Th2 cells and Treg/Th17 cells to attenuate allergic rhinitis. Autoimmunity. 2023 Dec;56(1):2189133. doi: 10.1080/08916934.2023.2189133. PMID: 36938614.
Shaik YB, Castellani ML, Perrella A, Conti F, Salini V, Tete S, Madhappan B, Vecchiet J, De Lutiis MA, Caraffa A, Cerulli G. Role of quercetin (a natural herbal compound) in allergy and inflammation. J Biol Regul Homeost Agents. 2006 Jul-Dec;20(3-4):47-52. PMID: 18187018.
Cesarone, M. R., Belcaro, G., Hu, S., et al. (2019). Supplementary prevention and management of asthma with quercetin phytosome: a pilot registry. Minerva Medica, 110(6), 524–529. https://doi.org/10.23736/S0026-4806.19.06319-5
Li, Y., Yao, J., Han, C., et al. (2016). Quercetin, Inflammation and Immunity. Nutrients, 8(3), 167. https://doi.org/10.3390/nu8030167
Bielory L, Gandhi R. Asthma and vitamin C. Ann Allergy. 1994 Aug;73(2):89-96; quiz 96-100. PMID: 8067602.
Johnston CS, Solomon RE, Corte C. Vitamin C depletion is associated with alterations in blood histamine and plasma free carnitine in adults.J Am Coll Nutr. 1996 Dec;15(6):586-91. doi: 10.1080/07315724.1996.10718634. PMID: 8951736.
